產(chǎn)品信息 TGF-β家族成員廣泛存在于從果蠅到人多種生物的 各種組織中,對正常細胞、癌變細胞都有著顯著作用。TGF-β除了影響細胞的增殖、分化,還在胚胎發(fā)育、胞外基質(zhì)形成、 骨的形成和重建等方面起著重要作用。 Dorsomorphin: A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2, ALK-3 and ALK-6). Also inhibits AMP-activated protein kinase (AMPK). 6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE Ref: Yu et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat. Chem. Biol. 4 33, 2008. Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request. Biological Activity: Not determined. 重慶市華雅干細胞技術(shù)有限公司 |